NEW : Postition available: Postdoctoral Researcher in Computational Structural Biology and Immunology
Welcome to the Schmidler research group web page. Members of the
group do theoretical and applied research in Bayesian statistics,
bioinformatics, and computational biology. Ongoing projects
in the areas of proteomics, molecular simulation, single-molecule
experiments, protein folding, and prediction of protein
structure and function are described under
Biology Projects. Our work on Monte Carlo
algorithms, change-point and segmentation
problems, statistical shape theory and datamining may be found under
Statistics Projects.
In addition, we have projects on computer-aided drug design and
biomaterials through various collaborations.
Scott Schmidler is Assistant Professor of Statistics and Decision Sciences at Duke University. Members of the group come from graduate and postdoctoral programs throughout the University and Medical Center, including Statistics, Mathematics, Computer Science, Engineering, and Biochemistry, as well as the Bioinformatics and Genome Technology program. Group resources include a shared 96-processor Beowulf cluster. Students interested in opportunities for rotation within the lab should send inquiries to scs@stat.
For inquiries from students outside Duke, please see Information for prospective students and postdocs.
Current projects in the group organized by biological area
or by statistical methodology:
Biology |
Statistics |
|||
| Protein Folding | Stochastic Segmentation | |||
| Proteomics | Statistical Shape Theory | |||
| Protein Structure Prediction | Monte Carlo Algorithms | |||
| 3D Structure Analysis and Function Prediction |
| Group members | |
| Collaborators |
Doug Brutlag -
Biochemistry Department, Stanford University Jun Liu - Statistics Department, Harvard University |
| Project Description | |
| Publications |
Schmidler SC, Liu JS, Brutlag DL (2001) Bayesian protein structure prediction Case Studies in Bayesian Statistics, Vol. 5, pp 363-378.
Schmidler, SC, Liu, JS, Brutlag, DL (2000) |
| Group members | Jen-hwa Chu, Jeff Krause |
| Collaborators | Terry Oas - Biochemistry Department, Duke University |
| Project Description | |
| Publications |
| Group members | Ben Cooke |
| Collaborators | |
| Project Description | |
| Publications |
| Group members | Casper Wu |
| Collaborators | Tim
Haystead - Pharmacology and Cancer Biology, Duke University Mike Datto - Pathology, Duke University |
| Project Description | |
| Publications |
| Group members | |
| Collaborators | |
| Project Description | |
| Publications |
Wu, TD, Schmidler, SC, Hastie, T, Brutlag, DL (1998) Regression analysis of multiple protein structures J. Comp. Biol., Vol 5, No 3, pp 597-607. (preprint version with color figures) Wu, TD, Schmidler, SC, Hastie, T, Brutlag, DL (1998) Modeling and superposition of multiple protein structures using affine transformations: analysis of the globins Pacific Symposium on Biocomputing '98 507-518 (color version) |