Title: Statistical Analysis of Neural Spike Train Data Abstract: There are two basic problems in the analysis of neural data. The "encoding" problem concerns how information is processed in neural spike trains; On the other hand , the "decoding" problem concerns how much information is in a spike train: in particular, how well can we estimate the stimulus that give rise to the spike train? Statistical models which builds a relationship between the stimulus and the instantiation of spike trains can provide a unified solution to these two coding problems in some cases. In this talk I will review some single neuron models, in particular, the integrate-and-fire model which is very simple but biophisically plausible. I will also describe recent work on various techniques for detecting functional connections between neurons and the nature of those connections. A multistate special event model will be proposed and the properties of the model will be discussed.