Prerequisites:
This course presupposes previous exposure to
mathematics and statistics at the level of the BGT program
prerequisites. In particular, students are expected to be prepared in
statistics at the level of STA-104 and
STA-114 and
in mathematics through the equivalent of MATH-103 and MATH-104.
Students uncertain about preparation are encouraged to contact the
instructor.
Goals:
This course covers fundamental
statistical theory and tools emphasizing applications arising in
computational molecular biology and functional genomics. This course
is also intended to adequately prepare students for advanced courses
on statistical genetics
(BGT 201), biological sequence analysis (BGT 203),
gene expression analysis
(BGT 208), and computational structural biology (BGT 207).
Grading
Course grades will be based on regular (weekly to
biweekly) assignments and an end-of-semester project. Computing
exercises will involve programming in R or (S-Plus).